Six of eight coveted awards granted by the Israel Science Foundation (ISF) have gone to researchers at Hadassah Hospital.

The ISF is an Israeli agency that supports breakthrough basic science in various fields of knowledge.

The grants provide money for research time and materials.  The awardees are all physician-scientists who not only take care of patients but work tirelessly in laboratories to uncover the causes of and potential cures for the diseases they treat.

This is one of the defining features of Hadassah, which has long promoted the idea of ‘the bedside to the laboratory’, by empowering doctors to conduct research using knowledge gained from their patients’ medical situation.

The Director-General of Hadassah, Prof Zeev Rotstein, says that success has come from doctors conducting “thorough, original, fact-based research and building intellectual and physical infrastructure that will last for years.

“These are busy physicians who spend a full day seeing patients and then engage in the basic research necessary to change the understanding of the diseases they see for all humankind. We are rightly proud of them.”

The six physician-scientist grant awardees are:

  • Thoracic Surgery Service head Ori Wald is targeting the immune suppressive microenvironmentof a relatively rare but aggressive form of cancer known as malignant pleural mesothelioma, which arises from the membrane covering the lungs and the inner side of the ribs, most frequently a result of inhaling asbestos.
  • Shai Rosenberg,a senior neuro-oncology physician, is using computers to create a machine-learning approach for precision medicine in his field.
  • Head of the Cardiac Insufficiency Unit Rabea Asleh is studying how the bacteria in the stomach can be used to regulate inflammation in cases of heart failure in which the left ventricle is not able to fill properly with blood.
  • Oncologist Albert Grinshpunis investigating DNA fragments released in the blood plasma of patients with colorectal cancer.
  • Inbal Reuveni,from the Department of Psychiatry, is investigating altered neural connections resulting from traumatic events in patients with PTSD.
  • Oncologist Tal Falick Michaeliis investigating cancer epigenetics.

Hadassah staff were also acknowledged in thirteen other categories, including research related to COVID-19.  Click here for a complete list.

“This success in basic research stands alongside the significant increase in clinical trials over the last few years,” says Prof. Rotstein, who adds that Hadassah is committed to “the best treatment for patients, fighting the virus with all our strength and simultaneously researching in various medical fields for a better future.”